Lady Jessica Atreides is the wife of Duke Leto Atreides and the mother of Paul Atreides – probably the biggest deal in the Duniverse. She is a Bene Gesserit and a big deal herself.

Jessica is also my favorite character from Dune, though I can’t be sure until I actually bother to read Dune.
There are a few reasons as to why. First, she scratches particular biases I have towards characters: she’s female and she’s depicted as loyal to the person she loves. Already, those are two great traits to have. On top of that, she’s a Bene Gesserit, who I think are just cool in general…but the most important thing that sets her apart from the rest of the cast is that she actually makes a human decision.
That decision being her choice to produce Paul, instead of following her orders. This is a big deal, because my understanding of the Dune story suggests that everyone is a pawn in plans that have been working in the background for centuries. But then she screwed everything up by having a son instead of a daughter. And her reason for screwing it up? Was it to put forward her own plan, like a certain other mother from a sci-fi franchise? No, it was just because she wanted to make the man she loves happy. As far as I’m aware, no other character in Dune ever makes a decision like that.^A) I am probably wrong, but I get the impression the narrative generally frowns upon these kinds of things and mostly treats characters poorly for making decisions that aren’t in accordance with grand philosophical designs. Rather, it feels like Jessica producing Paul wasn’t seen as an unexpected positive…but rather the result of a personality flaw.^B)

And I find that kinda annoying. I may elaborate further on this in the future.